LINC

LINC PHARMACEUTICALS

                           Anti-fibroticTechnologies

...breakthrough technology and a proven business strategy...


Current Demand for Therapeutics

The worldwide market for therapeutic drugs to treat chronic lung disease
is more than $17 billion per year.  The following are selected examples
of markets for individual drug products.
Disease
 Active Ingredient
 Current Sales
Bronchopulmonary
dysplasia
 poractant-alpha
poractant-alpha
 $ 20 million (US)
$ 37 million (EU)
Asthma/Emphysema
 salmeterol/fluticasone
salmeterol/fluticasone
zafirlukast
zafirlukast
tacrolimus
 $  3.2 billion (US)
$  3.2 billion (ex-US)
$ 140 million (US)
$   60 million (ex-EU)
$   80 million (US)
Idiopathic pulmonary
fibrosis
 pirfenidone
 $   64 million (JP)

Selected Markets for Current Therapeutic Agents